What household contaminants should concern me? You can choose a device with the right CADR for the contaminants you are targeting. These correspond to small-, medium-, and large-sized particles, respectively. Some air cleaners specify CADRs according to the three specific types of pollutants: tobacco The general rule is that the CADR of your air cleaner should be equal to at least two-thirds of the room’s area.įor wildfire smoke, the CADR should be higher, equal to the number of square feet of the room you are trying to clean. This is the amount of clean air your device will re-circulate. You want a filter that is at least MERV 13.Īnother important variable is the clean air delivery rate (CADR). This is usually expressed as a rating from MERV 12 to MERV 17. The effectiveness of a HEPA filter depends on how tightly bound the fibers are. Generally speaking, this type of particle includes pollen, dust, moisture, bacteria, viruses, and dirt. Your best choice to filter particles is a device with a HEPA filter, which is designed to collect at least 99.5% of particles in the air that are 3 microns or less in size. Probably the most important variable in an air purifier is the filter. To choose wisely, you have to know both the dimensions of the area you want to clean, the capabilities of the particular air purifier you’re considering, and what contaminants you’re targeting.īefore investing in an air purifier, you may want to invest in an air quality home test to determine what contaminants you have in your home. clean air delivery rate (CADR), or the amount of clean air they deliverĪll these variables are important in your consideration of a portable air purifier.how well they collect pollutants from indoor air (expressed as a percentage efficiency rate).how much air they draw through the filter (expressed in cubic feet per minute).If disease associated with cigarette smoking is recognized to be particle related, then certain aspects of the clinical presentation can be predicted this would include worsening of pulmonary function and progression of pathological changes and comorbidity (eg, emphysema and carcinogenesis) after smoking cessation since the particle is retained in the lung and the exposure continues.Īir pollution oxidants oxidative stress particulate matter smoking. Mechanistically, all particle exposures produce an oxidative stress, which is associated with a series of reactions, including an activation of kinase cascades and transcription factors, release of inflammatory mediators, and apoptosis. Individuals exposed to all these particles share a common clinical presentation with a loss of pulmonary function, increased bronchial hyperresponsiveness, pathologic changes of emphysema and fibrosis, and comorbidities, including cardiovascular disease, cerebrovascular disease, peripheral vascular disease, and cancers. There are numerous human exposures to other particles, and these vary widely in composition, absolute magnitude, and size of the particle. ![]() ![]() ![]() Smoking one cigarette exposes the human respiratory tract to between 15,000 and 40,000 μg particulate matter this is a carbonaceous product of an incomplete combustion. We propose that 1) injury and disease following cigarette smoking are associated with exposure to and retention of particles produced during smoking and 2) the biological effects of particles associated with cigarette smoking share a single mechanism of injury with all particles. The specific component responsible and the mechanistic pathway for increased human morbidity and mortality after cigarette smoking are yet to be delineated.
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